Epigenetic Regulation and Epigenomics

Epigenetics is a term in biology referring to heritable traits that do not involve changes in the underlying DNA sequence of the organism. Epigenetic traits exist on top of or in addition to the traditional molecular basis for inheritance.

Epigenetic Regulation and Epigenomics

Epigenetics is a term in biology referring to heritable traits that do not involve changes in the underlying DNA sequence of the organism. Epigenetic traits exist on top of or in addition to the traditional molecular basis for inheritance. The "epigenome" is a parallel to the word "genome," and refers to the overall epigenetic state of a cell. Cancer and stem cell research have gradually focused attention on these genome modifications. The molecular basis of epigenetics involves modifications to DNA and the chromatin proteins that associate with it. Methylation, for example, can silence a nearby gene and seems to be involved in some cancers. Epigenetics is beginning to form and take shape as a new scientific discipline, which will have a major impact on Medicine and essentially all fields of biology. Increasingly, researchers are unearthing links between epigenetics and a number of diseases. Although in recent years cancer has been the main focus of epigenetics, recent data suggests that epigenetic plays a critical role in psychology and psychopathology. It is being realized that normal behaviors such as maternal care and pathologies such as Schizophrenia and Alzheimer's might have an epigenetic basis. It is also becoming clear that nutrition and life experiences have epigenetic consequences. Discover more online content in the Encyclopedia of Molecular Cell Biology and Molecular Medicine.

More Books:

Epigenetic Regulation and Epigenomics
Language: en
Pages: 1254
Authors: Robert A. Meyers
Categories: Science
Type: BOOK - Published: 2012-05-29 - Publisher: John Wiley & Sons

Epigenetics is a term in biology referring to heritable traits that do not involve changes in the underlying DNA sequence of the organism. Epigenetic traits exist on top of or in addition to the traditional molecular basis for inheritance. The "epigenome" is a parallel to the word "genome," and refers
Epigenetic Regulation and Epigenomics
Language: en
Pages: 1254
Authors: Robert A. Meyers
Categories: Science
Type: BOOK - Published: 2012-10-02 - Publisher: John Wiley & Sons

Epigenetics is a term in biology referring to heritable traits that do not involve changes in the underlying DNA sequence of the organism. Epigenetic traits exist on top of or in addition to the traditional molecular basis for inheritance. The "epigenome" is a parallel to the word "genome," and refers
Plant Epigenetics and Epigenomics
Language: en
Pages: 245
Authors: Charles Spillane, Peter C. McKeown
Categories: Science
Type: BOOK - Published: 2016-08-27 - Publisher: Humana Press

Many fundamental discoveries concerning epigenetics and the elucidation of mechanisms of epigenetic regulation have developed from studies performed in plants. In Plant Epigenetics and Epigenomics: Methods and Protocols, leading scientists in the epigenetics field describe comprehensive techniques that have been developed to understand the plant epigenetic landscape. These include recently
Epigenetics in Health and Disease
Language: en
Pages: 608
Authors: Igor Kovalchuk, Olga Kovalchuk
Categories: Education
Type: BOOK - Published: 2012-05-22 - Publisher: FT Press

This is the first comprehensive, authoritative, and easy-to-understand introduction to modern epigenetics. Authored by two active researchers in the field, it introduces key concepts one step at a time, enabling students at all levels to benefit from it. The authors begin by presenting a historical overview that places epigenetics in
Epigenetics and Neuroplasticity - Evidence and Debate
Language: en
Pages: 250
Authors: Igor Kovalchuk, Olga Kovalchuk
Categories: Science
Type: BOOK - Published: 2014-11-05 - Publisher: Academic Press

The ‘epi-(Greek for ‘over’, ‘above’)genome’, with its rich cache of highly regulated, structural modifications—including DNA methylation, histone modifications and histone variants—defines the moldings and three-dimensional structures of the genomic material inside the cell nucleus and serves, literally, as a molecular bridge linking the environment to the genetic materials in our